摘要
It has been proposed that a major portion of ischemia-reperfusion injury is due to the generation of active oxygen radicalst. It has been demonstrated that free radical scavengers can protect the myocardium injured by reperfusion. But all Of them are indirect evidence for the generation of active oxygen radicals during ischemia and reperfusion. Electron spin resonance (ESR) is the most effective tecnique for the direct measurement of free radicals. But only a few reports have been found in literature so far. In this work, the ESR spectrum of the ischemic reperfusion of intact rabbit myocardium was directly measured at low temperature.
