摘要
Thirty-one multiple myeloma patients were classified chiefly by heavy and light chain detec-tion of myeloma protein (M protein).The results were as follows:19 out of the 31 casesbelonged to the IgG class,including the following subclasses—IgG1-λ.7;IgG1-k.5;IgG3-λ,1;IgG3-k,2;double M myeoma,2 (IgG3-λ+IgG2-k,IgG1-λ+IgG4-λ);IgG-λ,1;andIgG1-k 1.Seven cases were light chain diseases,of which 4 belonged to λ type.2 were k.and one was a double light chain disease.Five cases belonged to the IgA class (IgA-λ,3;IgA-k,2).We found no correlation between electrophoretic mobility and the antigenicity ofM protein even within subclasses,and the highly concentrated BJP in urine had a tendencyto form light chain polymers,possibly along different polymerization pathways.
Thirty-one multiple myeloma patients were classified chiefly by heavy and light chain detec- tion of myeloma protein (M protein).The results were as follows:19 out of the 31 cases belonged to the IgG class,including the following subclasses—IgG1-λ.7;IgG1-k.5; IgG3-λ,1;IgG3-k,2;double M myeoma,2 (IgG3-λ+IgG2-k,IgG1-λ+IgG4-λ);IgG-λ,1;and IgG1-k 1.Seven cases were light chain diseases,of which 4 belonged to λ type.2 were k. and one was a double light chain disease.Five cases belonged to the IgA class (IgA-λ,3; IgA-k,2).We found no correlation between electrophoretic mobility and the antigenicity of M protein even within subclasses,and the highly concentrated BJP in urine had a tendency to form light chain polymers,possibly along different polymerization pathways.
