稀土磺基水杨酸络合物与抑菌效应

Rare Earth Sulphosalicylate Complexes and Their Bacterostatic Effect

在无水乙醇介质中合成了3价(钅兰)、铈、镨、钕的磺基水杨酸络合物和4价铈的磺基水杨酸络合物。经元素分析、红外光谱、可见紫外光谱和热分析得知,Ce(Ⅲ)L·nH_2O 络合物,是一种含磺基水杨酸根、硝酸根的三结晶水的络合物,其组成是:Ce(Ⅲ)(C_7H_5O_6S)_2·NO_3·3H_2O,在60℃下脱水,312℃开始分解。Ce(Ⅳ)L’·nH_2O 络合物是一种含磺基水杨酸根、硝酸根和铵离子的六结晶水的络合物,其组成可能是:NH_4[Ce(Ⅳ)_2(C_7H_3O_6S)_2(C_7H_4O_6S)·NO_3]·6H_2O在62℃下脱水,在301℃开始分解。用平皿洞穴法研究了 La、Ce、Pr、Nd 等(钅兰)系元素的3价络合物对真菌的抑茵效应,它们的抑菌圈宽度超过22～35mm,均属于强的抑菌效应。

Sulphosalicylate complexes of cerium of different oxidation states were prepared in solid state and studied with reference to elemental analysis,UV absorption spectroscopy,IR absorption spectroscopy,thermogravimetry analysis(TG)and differential thermal analysis (DTA).It is found that the composition of the cerium complexes are[Ce(Ⅲ) (C_7H_5O_6S)_2·NO_3]·3H_2O and NH_4[Ce(Ⅳ)_2(C_7H_3O_6S)_2(C_7H_4O_6S)·NO)3]·6H_2O their are soluble in water.The rare earthelemelts(La(Ⅲ)、Ce(Ⅲ)、Pr(Ⅲ)、Nd(Ⅲ)) sulphosalicylate complexe have strong bacterostatic effect on Eubacteria.