血清钾水平在老年甲状腺机能亢进症治疗中的意义

Effect of serum kalium levels on the treatment of Graves disease in the elderly

随着我国人口的老化,老年甲状腺机能亢进症(简称老年甲亢)的发病率在逐年增加,且临床表现又千差万别,给临床诊断及治疗带来极大困难。我院从1982—01～1988—12末共收435名甲亢入院,其中老年甲亢26名占5.9％。2名患者入院后不久,因心跳骤停而死亡,死后血清钾报告为1.8和1.9mmol/L。

Different degrees of hypokalemia were examinied in 26 elderly patients with Graves' desease. Their serum kalium levels ranged from 1.8 to 3.4 mmol/L with 2.736±0.63 mmol/L as mean and SD.There were 42 adult patients with Graves' disease as control. Their serum kalium levels were 3.2 to 5.4 mmol/L,with 4.090±0.62 mmol/L as mean and SD(p<0.01).Sudden death was occurred in two of 26 patients due to hypokalemia. Their serum kalium levels were 1.8 and 1.9 mmol/L,with a mortality of 7.6％. The rest were cured because of giving kalii chloridum. It is found that the hypokalemia are markedly related to the degree and the course of Graves' disease. Immediate correction of hypokalemia plays an important role in the application of cardiac glycosides and diuretics and prevention of sudden death and also may be helpful to the treatment of Graves'disease.