C-反应蛋白检测鉴别细菌及病毒性肺炎的观察

SIGNIFICANCE OF THE PLASMA CRP LEVEL ON DIFFERENTIATION BETWEEN BACTERIAL AND VIRAL PNEUMONIAS

本文对70例支气管肺炎患儿做了C—反应蛋白(简称CRP)测定。结果:阳性29例(CRP>8200“g/L),阴性41例。阳性组治疗前白细胞计数升高(P<0.01)。阳性组治疗前后白细胞计数比较有显著差异(P<0.01)。两组病人对抗生素治疗效果及病程也都有显著差异(P<0.01P<0.05)。阳性组在肺炎好转过程中除1例阳性外均转为阴性,故CRP测定作为一项非特异性检查能较可靠地用于鉴别细菌及病毒性肺炎。

<ABSTRACT>The plasn a C-reactive protein levels were nonitored in 70 cases of the bronchial pneunonias.The results showed that the CRP level were increased at the acute staye of bacterical infections.The CRP rections were positive (CRP) 8200ug/L) in 29 cases and negative in 41 cases The total leuckocyte count was increased before treat ent in the positive group ( p<0.01 ). There was significant difference in the leukocyte cunt of the positive group between before and after treatnent (d<0.01).In the efficiency of the antibiotic thearpy or the length of the course of the diseases the significant defference existed between the two groups (p<0.001, p<0.05 respectively) .Except one patients, the CRP levels were decreased with the disappearance of symtoms, the CRP reactions all beconing negative in the positive group Therefore, the CRR level can be taken as a reliabe objective index for differentiation between bacterial and viral pneuonias.