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消炎痛治疗急性胰腺炎

Indomethacin Treatment of Acute Pancreatitis
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摘要 本文总结消炎痛治疗18例急性胰腺炎的临床效果;并以随机分组、接受常规治疗的29例病人作为对照,进行比较.结果表明:治疗组在退热、缓解疼痛、禁食以及住院天数等方面均明显短于对照组.对照组中有3例病人发展为出血坏死型胰腺炎;而治疗组无1例病情恶化,亦未发现消炎痛引起的不良反应.我们认为消炎痛能明显缓解急性胰腺炎病人的症状,防止病情进展、恶化,用于治疗急性胰腺炎安全而有效。 To examine the clinical effects of indomethacin on acute pancrea- titis (AP),47 patients with AP were randomly divided into two groups, the trial group (n=18) treated with indomethacin, 25mg thrice daily, for 7 days, and the control group (n=29) given ordinary treatment. The results Showed that the number of days with fever, pain, fasting and the median stay in hospital were significantly less in patients treated with indomethacin. In the control group, hemorrhagic pancreatitis had been developed in three patients, but in none in the trial group. Gastrointestinal bleeding or other side effects were not registered among indomethacin-treated patients. It is considered that indo- methacin is efficient and safe for treating AP.
出处 《临床消化病杂志》 1989年第1期15-18,共4页 Chinese Journal of Clinical Gastroenterology
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参考文献8

  • 1Taylor IL,et al.Factors That Modify the Effects of Prostaglandin on Diet-Induced Acute Pancretitis in Mice. Scandinavian Journal of Gastroenterology . 1985
  • 2Wedgwood KR,et al.2</sub>&amp;sid=Gastroenterology&amp;aufirst=Wedgwood KR');&#xA; ">A Model of Hemorrhagic Pancreatitis in CatsRole of 16, 16-Dimethyl Prostaglandin E<sub>2</sub>. Gastroenterology . 1986
  • 3Reber HA.Pancreatic Duct and Microvascular Permeability to Macromolecules.The Relation to Acute Pancreatitis. Scandinavian Journal of Gastroenterology . 1985
  • 4Harvey MH,et al.Vasoactive Drugs Microvascular Permability and Hemorrhagic Pancreatitis in Cats. Gastroenterology . 1987
  • 5Sanfey H,et al.Increased Capillary Permeability, An Early Lesion in Acute Pancreatitis. Journal of Surgery . 1984
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  • 8Ebbehoj N,et al.Indomethacin Treatment of Acute Pancreatitis-A Controlled Double-Blind Trial. Scandinavian Journal of Gastroenterology . 1985

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