摘要
本文指出,胃癌患者口腔标本念珠菌检出率(52.3％)明显高于其它肿瘤患者(21.5～24.5％)及正常人(4.1％),并在42.1％的胃癌切除标本中分离到念珠菌。来自胃癌患者的念珠菌与正常人口腔菌株和保藏菌株比较,对小白鼠具有更强的毒力,并可在小白鼠体内迅速扩散和侵入各主要器官。这些菌株对二性霉素B、制霉菌素、克念菌素及克霉唑等常用抗真菌药物表现了明显的抗药性。
This experiment Proved that candida in the mouth of gastric carcinoma Patients (52.3%) were detected obviously higher than that of the Patients of other tumor (21.5～23.0%) and normal man (4.1%), In the samples removed by operation from 42.1% gastric carcinoma, candida were detected. The virulence of the candida from gastric carcinoma is much stronger than that strains fo m the mouth of normal man and the Preserved strains, the candida diffused quickly in the bodies of the murines and invased main organs. The candida has obvious drug-resistance to antimycotic medicines most in use, such as amphotericin B、nystafin、cannitracin and clotrimazole.
出处
《中南医学科学杂志》
CAS
1989年第2期135-140,231-232+235-236,共10页
Medical Science Journal of Central South China
关键词
胃癌
念珠菌
念珠菌感染
gastric carcinoma
Candida
Candida infection
