脑脊液溶菌酶测定对中枢神经系统疾病的诊断价值

DIAGNOSTIC VALUE OF LYSOZYME ASSAY IN CEREBROSPINAL FLUID TO DISEASES OF CENTRAL NERVOUS SYSTEM

对部分病毒性脑膜炎(病毒脑)、化脓性脑膜炎(化脑)、结核性脑膜炎(结脑)、脑血栓形成等神经系统疾病患者进行了脑脊液(CSF)溶菌酶测定。结果表明:细菌性与非细菌性脑膜炎有显著性差别(P<0.01),对于结脑和化脑,由于病程不同,也有一定的鉴别价值。而脑血栓形成和脑出血患者,脑脊液溶菌酶含量与对照组比较无显著性差别(P>0.05)。新生儿败血症与新生儿败血症并发化脑患者之间,脑脊液溶菌酶含量有显著性差别(P<0.05)。因此脑脊液溶菌酶测定对上述疾病的诊断及鉴别诊断有较高价值。

The cerebrospinal fluid lysozyme in some patients with diseases of central nervovs system,such as viral meningitis,purulent meningitis,tuberculous meningitis and cere- bral infact et al.were determined.The results show that the lysozyme determination in bacterial and nonbacterial meningitis has significant difference (P<0.01),and it also possesses some values in the differential diagnosis between tuberculous and puru- lent meningitis because of their defferent process.The amount of lysozyme in cerebro- spinal fluid of cerebral hemorrhage and infarct has no significant difference compared to the control group (P>0.05),but those between children septicemia and its com- plicated purulent meningitis has significant difference (P<0.05).Therefore this test possesses a great diagnostic value in the diseases of central nervous system.