小鼠神经显示麻风病抗神经抗体的初步研究

THE PRELIMINARY STUDY OF USING RAT NERVE TO DEMONSTRATE ANTI-NEURAL ANTIBODY IN LEPROSY PATIENTS

本文检测28例各型麻风患者的抗神经抗体。28例各型患者中抗神经抗体阳性为25/28。这一结果揭示在多菌型患者抗体阳性频度和滴度水平有高於少菌型患者的趋势。对出现ENL反应的11例多菌型患者则未显示出其反应类型与抗神经抗体之间具有关系。有关麻风患者的型别、病期、及神经炎等与抗神经抗体频度和滴度之间的相互关系,有待进一步深入的研究才有可能加以阐明。

28 cases with different types of leprosy were studied to demonstrate anti-neural antibody in sera. The positive rate of the anti-neural antibody in all of the cases was 25/28. The frequency and titer of the positive of the antibody in lepromatous cases were higher than in tuberculoid cases, the trand was noticed in the study. The relationship between the reactive types and the titer of anti-neural antibody in the 11 lepromatous cases with ENL was not been found. It is necessary to enlarge the sample for further understanding the relatiomhip among the types, duration of leprosy, neuritis with titer, frequency of anti-neural antibody in different types of leprosy cases.