小儿轮状病毒的分子流行病学

MOLECULAR EPIDEMIOLOGY OF HUMAN ROTAVIRUS INFECTION IN INFANTS AND YOUNG CHILDREN

轮状病毒是小儿腹泻的主要病原之一。本文对1986～1987年间75例两岁以下的重症腹泻患儿的粪便进行了轮状病毒基因组的分离、鉴定及流行病学研究,发现1986年本地区流行的轮状病毒是以电泳型长型为主,而1987年则主要流行短型的轮状病毒,还发现一个混合感染的例子。

Rotavirus was identified in 51 of 75 children with seriousacute diarrhea during two years(1986—1987)period in Dalian.Threeelectropherotypes were identified.Two of them were“long”pattern and“short”one.Certain electropherotypes was found to be a major epide-mic strain in one years.One patient was shown to be mixedly infectedwith two prevalent electropherotypes.