影响暴发型流行性脑脊髓膜炎的预后因素

PROGNOSTIC FACTORS ON FULMINANT EPIDEMIC CEREBROSPINAL MENINGITIS

本文对近年来我院收治的暴发型流行性脑脊髓膜炎惠者5例,就其预后因素作了探讨。认为年龄、就诊时间、临床类型、多脏器功能衰竭及治疗方法诸因素对预后均有影响。资料表明,对暴发型流脑早期诊断及时治疗,要特别重视1岁以下及60岁以上患者的抢救。注意脑水肿。脑疝的早期表现:采取积极治疗措施;治疗原发病的同时,密切监测和保护各脏器功能,防止多脏器功能衰竭发生,可提高暴发型流脑的治愈率。

Fifty-one cases of fulminant epidemic cerebrospinal meningitis, including the shock type in 19, the cerebrol type in 22, and the mixed type in 10, are analysed in this papar. The prognosis of the patients was related to the following factors. 1. The mortality rate was much higher in the patients below 1 and over 60 years of age than in the rest (p<0.01). 2. The intervals between onset and treatment of the disease influence the prognosis of patients. The results of this paper show the sooner, the less. in mortality rates (p<0.01). 3. Both the meningitis type group and the mixed type group gave higher mortality rates than the shock type group (p<0.05). Cerebral edema, cerebral herniation, and/or a respiratory failure in brain origin seems to be the critical factors. 4. Twenty-four patients were complicated with a multiple organ. failure (MOF): of these. 13 died.