人类ABH抗原种属特异性研究

A Study of Specificity of Human ABH Antigen and Use of Species Identification

人类 ABH 红细胞血型抗原种属特异性从30年代起就有学者用人血清多克隆抗体和动物免疫多克隆抗体进行研究。他们发现某些动物的红细胞也有 ABH 抗原。这些动物的ABH 抗原能与多克隆抗体中部分抗体结合。根据对多克隆抗体 ABH

12 monoclonal antibody (McAb) include 5 anti-A,5 anti-B,1 anti- H and 1 anti-A+B,and polyclonal human serum anti-A andanti-B were test in parallel with more than 20 animal erythrocytes include pan troglodyles pango pygmaeus,monkey,cynoeephalus balouin etc.We found some McAb can discriminate all the measuing animals,that make it possi- ble to use McAb in species identification.McAb anti-A,anti-B and anti-H using in forensic sicence have two adventages:a)high specifi- city,some of them can discriminate primate animals.b) it can finish species identification and ABe groups measure in one procedure.