大白鼠A类初级传入纤维对脊髓背角会聚神经元C反应的抑制

THE INHIBITORY EFFECT OF A-PRIMARY AFFERENT FIBER ON C-REACTION OF DORSAL HORN IN THE RAT

实验是在用戊巴比妥麻醉后,基本清醒的大白鼠脊髓背角记录的,观察了由A反应和C反应所组成的会聚神经元的放电活动。统计了33个这类神经元C反应的基本参数。分析了A类初级传入纤维对C反应的抑制效应,此效应可用直线方程Y=ax+b(a≤0,b≥0)表示,并按Y值的大小将所受抑制的神经元分为强、弱两型。发现此抑制量同突触前抑制量呈高度正相关(P<0.01)。从而以脊髓背表面电位P波作为突触前抑制指标,证明了A类初级传入纤维对会聚神经元C反应的抑制中有突触前抑制的参与,并可能起主要作用。

Experiments were carried cut on the dorsal horn in conscious rats after being anesthetized with Numbarbital.Thirty-three convergent neuronactivities ccmposed of A—and C—reaction were recorded, and the substantial parameters of C—resction were attained.We analyzed the inhibitory effect of A—primary afferent fiber on C—reaction of convergent neurons.The inhibitory effect Could be expressed by a linear equation y=aX+b(a≤0, b≥0).The inhibitory neurons were divided into strong and weak groups according to the b—value.The correlation between inhibitory effect and p-waye of CDP was highly positive.This proves that presynaptic inhibition perhaps plays an important role in this kind of inhibition.