用力呼气中期流速对慢性阻塞性肺病早期诊断的探讨

AN EVALUATION OF FMF TO EARLY DIAGNOSIS OF PATIENTS WITH COPD

本文对156例COPD患者的CV/VC(％)与FMF作了相关性分析,求出了相关系数(r=0.6812,P<0.001)和直线回归方程式。两者呈中度负相关,说明CV/VC(％)随着FMF曲降低而增高。用此方程式计算的CV/VC(％)与实测的CV/VC(％)呈高度正相关(r=0.8935,P<0.001)。对另一组175例COPD患者的FEV_1％、FMF及推算和实测CV/VC(％)的异常率也进行了分析。结果表明FMF异常率均高于CV/VC(％)的计算值和实测值。在FEV_1％≥80％的患者中,FMF的敏感性也高于FEV_1％。作者认为FMF可作为COPD筛选和早期诊断可靠、敏感的一项指标。

The cv/vc％ and FMF of 156 cases with COPD were analysed. The equation of linear regression was formed and showed negative correlation (r=-0.6812, P<0.001). Using above-mention equation, cv/vc ％ was deduced. The deduced cv/vc％ and measured cv/vc％ showed better positive correlation(r=0.8935, P<0.001). The abnormalities of FEV_1％, FMF, deduced cv/vc％ and measured cv/vc％ in another group (175 cases)were analysed. The results showed that the percentage of FMF abnormality was higher than deduced cv/vc％ and measured cv/vc％. In the group of FEV_1％≥80％, the sensitively of FMF was higher than FEV_1％. The authers concluded that FMF is a sensitive and reliable index for selecting and early diagnosing COPD patients.