摘要
对南海小棒短指软珊瑚Sinularia microclavata的提纯物(24-methylemechclestcrol)进行药理研究,证明该经化合物具有降血压、减慢心率、抗心律失常、对血管条的解痉作用,对实验动物具有耐缺氧的一系列生理活性,对离体回肠平滑肌有解痉作用。结果提示,小棒短指软珊瑚的提纯化合物(24-亚甲基-胆固醇)有开发多种药用的前景。
A study was conducted on physical activities of extract (24-methylene-cholesterol) from the soft coral (sinularia microclavata) collected from South China Sea. The results showed that the extract had effects on perfusion in isolated hearts of rabbits,weakening of heart rate and abatement of myocardial contraction. The extract has suppressive effects on contraction of the removed aorta and ileums in rabbits. It also has an antiarrhythmic effect induced by aconite and could prolong the survival time of mice in hypoxia.
出处
《热带海洋学报》
CAS
CSCD
1989年第3期68-74,共7页
Journal of Tropical Oceanography
基金
国家自然科学基金资助项目
