腹内感染的细菌学研究

The Bacteriology of Intra-Abdominal Infections

本文对外科腹内感染150例进行了需氧与厌氧的细菌学研究。结果表明腹内感染的病原菌都是消化道内的正常菌群,需氧菌以大肠杆菌等革兰氏阴性杆菌为主,而厌氧菌则以吉氏拟杆菌等脆弱群拟杆菌多见。感染多为几种细菌的混合感染,尤其是需氧菌与厌氧菌的混合感染。并对内源性细菌引起感染的致病机理进行了讨论。

The bacteriology of intra-abdominal infections was studied prospectively in 150patients. Special techniques (Gas Pak) for isolating anaerobes were employed along with standard methods for isolating aerobes. There are total of 395 isolates in 117 of 150 cases. Of these, 198 were facultive anaerobes or strict aerobes in 112 of 150 cases. The remaining were anaerobes in 74 of 150 cases. Gramnegative bacilli made up 80.8％ of all aerobes isolated and E. coli was isolated most commonly (93 strain, 47.0% of all aerobes).Bacteroides fragilis groups were isolated most eommouly in all anaerobes(70 strain, 35.5% of all anaerobes)and B. distasonis was isolated most frequently in this groups (48 strains, 68.6% of this groups). The majority of cases were mixed infected involved both aerobes and anaerobes(69 cases, 59.0% of all positive cultures). The results showed that all the organisms isolated were the normal flora of digestive tract. The most important organiams that caused intraabdominal infections were E.coli and B. distasonis. The cooperative action was performed by aerobes and anaerobes in the infections.