金荞麦的致突变和抗突变研究

Studies on Mutagenicity and Anti-Mutation of Fagopyrum cymosum (Trev) Meisn

本文用Ames法对金荞麦的致突变和抗突变性进行了研究。结果表明:金荞麦在0.001mg/皿—5mg/皿7个剂量未发现阳性突变反应,并对正定霉素和甲基甲烷磺酸酯所诱发TA98和TA100菌株的突变,具有抗突变的作用。

The paper reports the studies on mutagenici,ty and anti-mutation of the Fagopyrum cymosum (Trev) Meisn in Ames test. The result shows that, under the condition of+ S9mix, all of the six positive mutagens can induce the reversion of the mutation strains of TA97, TA98, TA100 and TA102 with the presence of dose-respond curve, but Fagopyrum cymosum (Trev) Meisn dissolve in DMSO, and it hasn't caused any mutation within the seven doses of 0.001-5mg/culture dish. On contrary, it may inhibit the mutation of strains of TA98 and TA100 induced by Daunomycin and Methyl Methane Sulfonate.