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冬虫夏草抗炎作用机理的初步研究 被引量:5

MECHANISM ON ANTIINFLAMMATORY EFFECT OF CORDYCEPS SINENSIS (BERK) SACC.
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摘要 我们曾报告虫草对巴豆油诱发的小鼠耳部炎症、大鼠蛋清性足肿胀及棉球肉芽肿等均有明显的抗炎效果,本文进一步分析了冬虫夏草抗炎作用的机理,现将结果报告于下。材料与方法一、冬虫夏草水提液:冬虫夏草为青海省玉树州昂久县出产,用蒸馏水80℃±2℃提取2次,再煮沸提取一次,合并3次滤液,减压过滤,在80℃下浓缩至1g/ml。二、实验方法:瑞士种小鼠体重29—30g。 This paper reports mechanism on antiinflammatory effect of Cordyceps sinensis (Berk) Sacc. The adrenal weight and cholesterol content of adrenal, plasma level of hydrocortisoae and aldosterone in experimental group were obviously higher than the control group. The hyperplasia of the zona glomerulosa, zona fascieulata and zona reticularis of adrenal cortex in the rats were observed by electron microscope. The zona gromerulosa cells of experimental group contained a large of mitochondria, lipid droplets and smooth encoplasmic reticu-lum membrane vesicles in the cytoplasm by stercological analysis. It is suggested that Cordyceps sinensis (Berk) Sacc has facilitation and potentiation of synthesis and excretion of cortical hormone. Therefore; it exerts antiinflammatory effect.
出处 《中药药理与临床》 CAS CSCD 1989年第2期29-31,4,共4页 Pharmacology and Clinics of Chinese Materia Medica
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参考文献2

  • 1叶于聪,陈钦铭,柴风玲,周生祥,海平,金凯平.青海冬虫夏草菌丝的药理研究[J]青海医药杂志,1988(01).
  • 2陈钦铭,叶于聪,寇星灿,许子俊,王志刚,熊素梅,方明明,阎风菊.直茎紫堇对细粒棘球蚴作用的电镜观察[J]药学学报,1985(05).

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