电刺激照射后大鼠摄食中枢和饱中枢时胃运动的反应

EFFECTS OF STIMULATION OF THE FEEDING AND SATIETY CENTRES ON GASTRIC MOTILITY AFTER IRRADIATION IN RATS

本实验观察了8Gyγ线照射后大鼠摄食中枢、饱中枢的自发放电变化及电刺激这两个中枢时胃运动的反应.结果如下:8Gy γ线照射后大鼠的摄食中枢、饱中枢的自发放电与对照无差别;刺激正常大鼠的饱中枢主要出现胃运动的抑制反应,而刺激摄食中枢则主要出现胃运动的兴奋反应;8Gy γ线照射后2、3、4天刺激大鼠的饱中枢和摄食中枢都出现胃运动的抑制反应.

The effects of the feeding and satiety centres on gastric motility were studied in anesthetized rats by electrically stimulating these centres and recording the intragastric pressure.The results were as follows:1.There was no difference in the spontaneous discharges of the feeding and satiety centres between 8 Gy irradiated rats and the controls. 2.Stimulation of the satiety centre elicited chiefly inhibition,whereas that of the feeding centre excitation of gastric motility in normal rats.3.On the 2nd to 4th day after 8Gy irradiation stimulation of both the feeding and satiety centres usually revealed inhibition of gastric motility.The above results iudicate that the inhibition of gastric motility after irradiation is independent of the activities of feeding and satiety centres.