食管鳞癌血型抗原变化,DNA含量改变与病理形态学的关系

CHANGES OF BGA EXPRESSION,DNA CONTENT RELATED TO PATHOLOGICAL MORPHOLOGY IN ESOPHAGEAL CARCINOMA

应用免疫组化及FCM方法研究食管鳞癌血型抗原表达和DNA含量并分析与病理形态学的关系。发现,血型抗原表达阳性的二倍体肿瘤多分化较好,表现为团块状或网状生长且很少发生转移。因此,血型抗原表达的变化,DNA含量的改变可以反映食管癌的恶性程度。

Immunohistochemical and FCM methods were used to research on the relation-ship of BGA expression and DNA content to pathological morphology in esophagealcarcinoma. The results showed: diploidy carcinoma which expressed positive BGAwere well differentiation, thick massive or reticular growth pattern and fewermetastasis. So, the changes of BGA expression and DNA content can reflect thedegree of malignancy in esophageal carcinoma.