正常人及某些肿瘤病人血清脂质过氧化物含量的研究

THE SERUM LIPOPEROXIDE LEVEL IN NORMAL HEALTH AND SOME PATIENTS WITH MALIGNANCIES

为探讨血清脂质过氧化物含量与肿瘤的关系,本文采用TBA化学比色法时119例30～70岁的健康人和100例胃癌、食管癌、乳腺癌、肺癌和子宫肌瘤患者血清脂质过氧化物含量进行了分析测定。结果表明:(1)血清脂质过氧化物含量随增龄而增加,60～岁组与30～岁和40～岁组比较均有统计学意义(P<0.01);50～岁组与30～岁组比较亦有意义(P<0.05);(2)各肿瘤病人组与同龄健康人比较有显著性差异(子宫肌瘤组为P<0.05,其余组均为P<0.01)。本研究提示,脂质过氧化物含量与肿瘤密切相关。

The serum lipoperoxide level in 119 normal subjects and 100 patients withvarious malignancies were measured by TBA colorimetry. we found out that(1)Thelevel of lipoperoxide was arise concomitantly with age increasing,such asthe difference among 60-year group, 30-year group and 40-year group was mostsignificantly (P<0.01) and ages between 50-year group and 30-year group wasalso had significances too. (2) The differences between all cancer groups andcontrol groups were significantly (P<0.01), but in hysteromyoma group P<0.05, this resuit indicated that lipoperoxide level was close interrelated withcancers.