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ANISODAMINE INHIBITS ENDOTOXIN-INDUCED PROSTAGLANDINS AND LEUKOTRIENES RELEASE FROM MOUSE MACROPHAGES

ANISODAMINE INHIBITS ENDOTOXIN-INDUCED PROSTAGLANDINS AND LEUKOTRIENES RELEASE FROM MOUSE MACROPHAGES
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摘要 It was reported that anisodamine (654-2)reduced thromboxane synthesis by platelets and lowered the plasma prostaglandin level in endotoxic shock animals when administered in the early phase of shock. However, the exact relationship between arachidonic acid (AA) metabolism and the effects of 654-2 has not been completely understood. We found that 654-2 decreased acetylcholine-and norepinephrine-induced PG release from rabbit iris,
作者 麦凯 岳天立
出处 《Chinese Science Bulletin》 SCIE EI CAS 1989年第24期2061-2066,共6页
基金 Project supported by the National Natural Science Foundation of China
关键词 arachidonic acids PROSTAGLANDINS LEUKOTRIENES MACROPHAGES endotoxin. arachidonic acids, prostaglandins leukotrienes macrophages endotoxin.
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