摘要
The authors studied 24 cases of refractory prema-ture beats by giving 0.1 adonisidum twice daily withHolter’s monitoring.It was found that adonisidumwas effective in 12 cases (P【0.001),or 50%.In another 8 patients adonisidum or mexiletinealone were ineffective for premature beats.However,when these patients were treated with both mexiletineand adonisidum,they responded with no exception(P【0.001).
The authors studied 24 cases of refractory prema- ture beats by giving 0.1 adonisidum twice daily with Holter's monitoring.It was found that adonisidum was effective in 12 cases (P<0.001),or 50%. In another 8 patients adonisidum or mexiletine alone were ineffective for premature beats.However, when these patients were treated with both mexiletine and adonisidum,they responded with no exception (P<0.001),or 50%. In another 8 patients adonisidum or mexiletine alone were ineffective for premature beats.However,when these patients were treated with both mexiletine and adomisidum,they responded with no exception(P<0.001).All 7 cases monitored with one hour Holter recording responded to adonisidum(P<0.001).As adonisidum tends to slow the heart rate,it is especially indicated for patients suffering from premature beats with increased heart rate,and should be used with caution in cases with slow heart rate or A-V block.