摘要
Sixteen alkaloids have been isolated from the fruits of Kopsia officinalis Tsiang and P.T. Li(Apocynaceae), a plant commonly used in folk medicine for treating tonsillitis and rheumatism. Ten of them were identified as known alkaloids-eburnamenine(1), kopsanone(2), 5, 18-dioxokopsan (3), kopsinilam(4), kopsinine(5), pleiocarpine(6), kopsamine(7), N-carbomethoxy-12-methoxykop- sinaline(8), N-carbomethoxy-11, 12-dimethoxykopsinaline (9) and(+)-vincadifformine (13). The other three have now been proved to be new. They are N-carbomethoxy-11-hydroxy-12-methoxy- kopsinaline(10), N-carbomethoxy-11-methoxy-12-hydroxykopsinanne (11) and kopsamine N-oxide (12).
Sixteen alkaloids have been isolated from the fruits of Kopsia officinalis Tsiang and P.T. Li(Apocynaceae), a plant commonly used in folk medicine for treating tonsillitis and rheumatism. Ten of them were identified as known alkaloids-eburnamenine(1), kopsanone(2), 5, 18-dioxokopsan (3), kopsinilam(4), kopsinine(5), pleiocarpine(6), kopsamine(7), N-carbomethoxy-12-methoxykop- sinaline(8), N-carbomethoxy-11, 12-dimethoxykopsinaline (9) and(+)-vincadifformine (13). The other three have now been proved to be new. They are N-carbomethoxy-11-hydroxy-12-methoxy- kopsinaline(10), N-carbomethoxy-11-methoxy-12-hydroxykopsinanne (11) and kopsamine N-oxide (12).
