86例胰腺癌分析

ANALYSIS OF 86 CASES OF PANCERTIC CANCER

胰腺癌的发病率逐年增加,目前约占消化道肿瘤的1％左右。胰腺癌早期无症状,故诊断困难,手术切除率也低。本文总结了1975～1985年收治的86例胰腺癌,其中胰头癌65例,胰体尾部癌21例,其肿瘤切除率分别为26.1％和23.9％。胰十二指肠切除术后5年生存率为17.6％,胰体尾部切除术后2年生存率为40％,姑息性手术后平均生存10个月。还讨论了有关胰腺癌的诊断和治疗,以及影响预后的因素。指出,凡有胰腺被膜受侵、胰腺周围淋巴结转移、肿瘤周围组织中血管受侵、肿瘤侵犯邻近脏器、组织学类型以及远方转移等,都直接影响预后。本组肿瘤切除病例,术后发生胰瘘者仅2例(9.1％),经治疗全部愈合。

The incidence of pancreatic cancer is on the increase and it now represents 1% of all neoplasm of the gastrointestinal tract. Early pancreatic cancer is difficult to diagnose since it may be asymtomatic. The rate of operative resection was lower. 86 cases of pancreatic cancer were collected and analyzed from 1975——1985. 65 cases of the tumor were located in the head of the pancreas. In 21 cases, the tumor were located in the body and tail of pancreas with the resectability rate of 26.1% and 23.90%, respectively. Five years survival rate was 17.6% after panceratoduodenectomy and two years survival rate was 40% after resection of body and tail of the pancreas. The mean survival period was 10 months for those who underwent a initial palliative operation. The diagnosis and treatment of pancreatic cancer and the factore of influence prognosis were discussed.