摘要
心肌显象剂^(99m)Tc-TBI Ⅱ期临床试验共观察了正常人22例和各类心脏病患者120例。结果表明^(99m)Tc-TBI制备简便,使用安全,静态心肌显像的效果与经典的^(201)Ti基本相同,可用于对心肌梗塞的诊断和定位,运动负荷显像能鉴别心肌梗塞和心肌缺血。由于此药在肝脏有较高的聚集,在心肌平面彫像上,影响对左心室下壁和后壁的观察,尤其在LAO70°有63.5%(80/126)下壁观察不清;断层显像基本上避免了肝影干扰,对心梗病变的检出率达心电图的170%,故本显像剂更宜于心肌断层显像。
99mTc-TBI in 10 normal volunteers were studied in clinical trial I. The results showed that 99mTc-TBl was easily-prepared,safe and effective as a myocardial perfusion agent. Inferior and posterior wall of heart was difficult to observe in planar imaging because of the contribution of liver. but we could get satified results in tomographic imaging.
出处
《北京大学学报(医学版)》
CAS
CSCD
1989年第S1期43-45,101,共4页
Journal of Peking University:Health Sciences