卵巢癌患者^(111)In-OC125的放射免疫显像

IMMUNOSCINTIGRAPHY OF ^(111)IN-LABELED MONOCLONAL ANTIBODY OC125 IN PATIENTS WITH OVARIAN CANCER

9例卵巢癌术后、血清CA125升高的患者,用^(111)In-OC125放射免疫显像(RIS)判断复发或转移。4例经二次手术和CT证实的RIS阳性者中有3例是RIS首先发现复发或转移。5例RIS阴性者,3例证实为真阴性,2例为假阴性,RIS诊断正确为7/9。提示RIS可能作为判断卵巢癌及其复发转移的重要方法。

111In-OC125 Radioimmunocintigraphy(RIS) were performed to determind whether recurrence or metastas'es of carcinoma in 9 patients with ovarian cancer whose serum CA125 increased after operation. RIS detected recurrence or metastatic lesions in three out of four patients with RIS Positive.CT scan positive and surgical confirmation. Three out of five RIS negative were true negative. Two were false negative. The accuracy was 7/9. This indicateds that RIS may be a important method in locating primary lesion and detecting recorrenc or metastatic focus.