早期高压氧治疗对急性颅脑外伤患者失语症的疗效观察

Effects of early hyperbaric oxygen therapy on alogia in acute cerebral injury

目的研究早期高压氧（HBO）治疗对急性颅脑外伤患者失语症的疗效。方法将2004年1月至2007年8月在我院住院的62例急性颅脑外伤患者分为HBO治疗组和常规治疗组，常规治疗组采用临床常规治疗，HBO治疗组在常规治疗的基础上，实施24～48次HBO治疗，并且在治疗结束后1年内每3个月进行1次随访。在治疗前、后分别采用西方失语成套测试法（western aphasia，WAB）检测并进行CT检查，对他们的语言功能和恢复情况进行评价和比较。结果HBO治疗组显效率（83．8％）显著高于常规治疗组（54．8％），经，检验P〈0．05；CT检查证实患者病变部位阻塞的血管已经恢复再通或已获得重建。结论早期HBO治疗有利于促进或恢复患者的语言功能。

Objective To investigate the effects of early hyperbaric oxygen therapy on aphasia in acute cerebral injury. Methods Sixty-two patients with acute cerebral injury were admitted into the hospital from January 2004 to August 2007. They were randomly divided into the hyperbaric oxygen （HBO） group and the control group. The control group was administered with routine treatment other than HBO, while the HBO group was given 24-48 sessions of HBO treatment in addition to routine treatment. To know how they recovered, clinical follow-ups were made every 3 months, one year after the patients terminated treatment. The linguistic function of the patients was evaluated and compared by using Western Aphasia Battery （WAB） and CT before and after HBO therapy. Results Results showed that the HBO exposure group had obviously better results when it was compared with the control group （ 83. 8% ： 54. 8% ）. And test showed that P 〈 0. 05. CT examination demonstrated that the blocked vessels in the affected area were either recovered or repaired. Conclusions Early HBO therapy will help to improve or recover the linguistic function of patients with acute cerebral injury.