苏州市学龄前儿童空肠结肠弯曲菌感染血清流行病学调查

Seroepidemiologieal Investigation of Campylobacter Jejuni/Coli Infections in Preschool-Aged Children in Suzhou

本文采用 ELISA 方法,对苏州市学龄前儿童弯曲菌感染进行血清流行病学调查.结果表明,抗弯曲菌特异性 IgG 抗体阳性率为54.65%,性别差异无统计学意义.抗体阳性率随年龄的升高而增加,<2岁组阳性率为22.22%,2～岁组为59.38%,显著高于<2岁组(P<0.001);4～岁组阳性率为72.5%,较2～岁组为高,但两者无统计学差异(P>0.1),似乎具有稳定趋势,值得进一步探讨。本调查还表明,<2～5岁组 IgG 抗体水平低,2～岁组达较高水平,此后呈下降趋势。说明<2岁组对弯曲菌感染的免疫力弱,预防重点应放在该年龄组.

The positivity rates of the specific serum IgG in preschool-aged children were 54.65% (94/172).The rates of the difference between the female and male has no statistical signifi- cance.The positivity rates increase with age,it is 22.22% in the～2 age group and 59.38% in the 2～ age group.The differences between the two groups are significant (P<0.001). The positivity rate in the 4～ age group is 72.5%, higher than that in the 2～ age group,but no differences in the statistic analysis(P>0.1).The results suggest that the positivity rates elevating after 4 ages appeare to be stable.This deserve further study.The serum IgG level elevates with age,it is low in the～2 age group,and increases linearly in the 2～5 age group and then falls.These data show that the immunity from campylobacter in the～2 age group is weak,and the attention of the preventive measures should be paid mainly to his age group children.