摘要
本文使用DNS-CI 荧光试剂-聚酰胺薄膜层析法,分析糖尿病、甲状腺机能亢进症、甲状腺机能减退症和肥胖症患者血浆游离氨基酸,并与正常人比较.结果:糖尿病者的支链氨基酸明显升高,甲亢者的酪氨酸和羟脯氨酸明显升高,甲减者此2种氨基酸明显降低,肥胖症者的生酮氨基酸明显升高.说明内分泌功能紊乱能导致氨基酸代谢异常.经多元逐步回归分析。
Plasma free amino acid concentrations were measured in 127 patients with endorcine
disease of varous aetiology.All results were compared with those in 29 control subjects.In
patients with diabetes mellitur plasma concentrations of branched chain amino acid were
significantly increased.Patients with hyperthnoidism plasma concentrarions of tyrosine and
hydroxyproline were significantly reduced.In patients with myxoedma plasma concentra-
tions of tyrosine and hydroxyproline were significantly increased.In patients with obesity
plasma concentrations of ketogenic amino acid were significantly increased.Most changes
in patients with endocrine disease may be explained on the basis of endocrine dysfunction and abnormal amino acid metabolism.
出处
《苏州大学学报（医学版）》
CAS
1989年第2期123-126,170-171,共6页
Suzhou University Journal of Medical Science
