摘要
In the present study, T lymphocyte subsets, NK and ADCC activity, and lymphocytetransformation rate (LT) were investigated by flow cytornetry and micro- LDH relcasing test in 67paticnts with hepatocellular carcinoma(HCC) and the relationship between changes of host immuni-ty after operation and tumor (?) were, further explored by follow-up study and generalanalysis. The results indicated that host immunosuppression became more severe in two weeks af-ter operation and then, gradually relurned to the level before opcration—"postoperativeimmunosuppressive period". Recovery time of postoperative immunosuppressive period andimmunc function condition of host after operation were closcly correlated with HCC recurrence rate.After operation, intensive immunologic examination can provide a valuable reference for finding highrisk population with turnor rccurrence and perfonning an effective postoperative immunotherapyagainst tumor rocurrence at (?)stage.
In the present study, T lymphocyte subsets, NK and ADCC activity, and lymphocyte transformation rate (LT) were investigated by flow cytornetry and micro- LDH relcasing test in 67 paticnts with hepatocellular carcinoma(HCC) and the relationship between changes of host immuni- ty after operation and tumor were, further explored by follow-up study and general analysis. The results indicated that host immunosuppression became more severe in two weeks af- ter operation and then, gradually relurned to the level before opcration—'postoperative immunosuppressive period'. Recovery time of postoperative immunosuppressive period and immunc function condition of host after operation were closcly correlated with HCC recurrence rate. After operation, intensive immunologic examination can provide a valuable reference for finding high risk population with turnor rccurrence and perfonning an effective postoperative immunotherapy against tumor rocurrence at stage.
