重症病毒性肝炎并发多系统脏器衰竭102例临床分析

Severe viral hepatitis complicated with MSOF: Clinical analysis of 102 cases

本文报道了102例重症肝炎并发多系统脏器衰竭(MSOF)。重症肝炎并发MSOF的发生率为102/136(75％),病死率为82.3％。肝炎病毒不仅损害肝脏而且可直接或间接损害中枢神经系统、凝血系统以及心、肺、肾等器官。重症肝炎是导致发生MSOF的重要因素之一。本文对不同类型重症肝炎并发MSOF的各系统脏器衰竭出现的频度、顺序、脏器衰竭数目与预后的关系等临床特点做了分析,并对重症肝炎并发MSOF的机制做了阐述。

102 cases of severe hepatitis complicated with MSOF were reported. The incidence of MSOF due to severe hepatitis was 75% (102/ 136), and the mortality rate was 82. 3%. Hepatitis virus not only causes liver damage but also causes damage to the central nervous system, coagulation system, heart, lung, kidney and other organs. Severe hepatitis is one of the main causes of MSOF. The clinical characteristics of severe hepatitis complicated with MSOF,such as the frequency and sequence of the various organ system failure,and the relationship between the the prognosis and the number of organ failure in different types of severe hepatitis were analyzed, and the pathogenesis of severe hepatitis complicated with MSOF was discussed.