654—2对内毒素休克鼠血浆纤维连接蛋白的影响

Effect of anisodamine on the plasma fibronectin in rats with endotoxic shock

本文采用大肠杆菌内毒素所致的大白鼠休克模型,观察了血浆纤维连接蛋白、网状内皮系统吞噬功能的变化。结果表明:内毒素休克时血浆纤维连接蛋白降低,网状内皮系统吞噬功能受抑制,两者明显相关。同时观察到654—2对此有保护作用。

The change of plasma fibronectin and pohagocytic function of the reticuloendothelial system (RES) was observed in rats with shock induced by E.coli suspension (endotoxin).The result showed that the decrease of plasma fibronectin and the inhibition of the phagocytic function of RES in endotoxic shock were significantly cor related.The administration of anisodamine was found to have a protective effect on this change in septic shock.