口腔鳞癌24例治疗总结

TREATMENT OF 241 PATIENTS WITH SQUAMOUS CELL CARCINOMA IN THE ORAL CAVITY

本院自1975年7月至1985年12月共收治口腔鳞癌241例。放射治疗为主要治疗手段,本文作一回顾性分析。

In a series of 241 patients with squamous cell carcinoma of the oral cavity treated during 1975 to 1985, 13 patients were treated by resection, 175 radiotherapy alone, 37 postoperative radiotherapy, 11 postoperative radiotherapy for recurrent lesions, 2 preoperative radiotherapy and 2 chemotherapy. The 5 year follow-up rate was 92.9%. The 1, 3 and 5 year survival rates were 60.6%, 28.2% and 22.3%, respectively. Prognostic factors were analysed. In this series, the 5 year survival rates of the mobile tongue, gingiva, hard palate, floor of the mouth and buccal mucosa were 20.6%, 32%, 21.7%, 30.8% and 18.2%. The 5 year survival rates of Ⅰ-Ⅳ stage lesions were 90.6%, 44.4%, 19.6% and 9% (p<0.05). The 5 year survival rate of patients who received 7100-8000 cGy was 26.1%. Radical doses ranging from 7000-8000 cGy are considered to b'e suitable.The chief cause of failure was local recurrence.