性腺恶性淋巴瘤的治疗——附10例报告

PRIMARY MALIGNANT LYMPHOMA OF THE GONAD——Report on 10 Patients

自1966年国外等报告原发于性腺的恶性淋巴瘤258例(睾丸212例,卵巢46例),国内报告71例(睾丸68例,卵巢3例)。其诊断的标准是:1.诊断时发病的瘤块在性腺;2.有肯定的病理组织学诊断;3.生存者随诊在6个月以上。本院自1980年到1987年2月共收治10例,现分析其临床表现、治疗方法与预后。

Ten patients with primary malignant lymphoma in the gonad (testis 7, ovary 3) are reported. The pathological classification was all non-Hodgkin's lymphoma, diffuse type, large cell predominant. Clinical staging showed 6 patients had Stage ⅠEA, one had Stage ⅡEA in the male, and 2 patients had Stage ⅡEA and one had Stage ⅣEA in the female. The 2 and 5 year survivals were 7/7 and 2/2 with an average survival time of 51 months in the male and 22 months in the female. Radical orchiectomy or ophorectomy may not be enough for this disease. It should be followed by radiotherapy or chemotherapy. This treatment protocol is as true in the testicular lymphoma as in the ovarian lymphoma. For radiotherapy, inverted Y field was usually used, to tumor doses of 40 to 50 Gy in 6 to 8 weeks. For chemotherapy, BACOP was preferred.