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微孔滤膜法测定小鼠淋巴细胞白血病L_(1210)细胞DNA单链断裂与修复

SINGLE-STRAND BREAK AND REJOINING OF DNA IN X-RAY INDUCED MOUSE LEUKEMIA L1210 CELLS
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摘要 DNA是细胞遗传及生长繁殖的物质基础。DNA的结构损伤直接影响了细胞的各种生物学功能。 The X-ray induced mouse leukemia L1210 cell DNA single strand break and rejoining were studied by improved membrane filtration method. The results showed that X-ray irradiation could induce L1210 cell DNA single strand break and a linear relationship between X-ray dose and DNA single strand break was observed. Under proper conditions, the broken DNA single strand could rejoin. The influencing factors in this method are also studied.
出处 《中华放射肿瘤学杂志》 CSCD 1989年第2期42-44,41,共4页 Chinese Journal of Radiation Oncology
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  • 1陈去恶,周启玲,邢国仁,郑德存,柳青梅.家用压力锅改装为除菌过滤用耐压容器[J]生物化学与生物物理进展,1985(05).
  • 2孟祥顺,郑秀龙.过热对细胞DNA辐射损伤与修复的影响Ⅰ 滤膜—荧光法及其在DNA结构检测中的应用[J]辐射研究与辐射工艺学报,1984(03).

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