踝臂指数对新疆维吾尔族人冠状动脉狭窄程度的预测价值

Value of Ankle Brachial Index to Predict the Extent of Coronary Stenosis in Xinjiang Uyghur People

目的观察新疆维吾尔族患者踝臂指数与冠状动脉狭窄程度的相关性,评价踝臂指数对新疆维吾尔族患者冠状动脉狭窄程度的预测价值。方法对114例连续入选冠状动脉造影患者进行踝臂指数测量、病史采集及血液生化检查。结果踝臂指数与Gensini评分呈显著负相关(r=-0.6941,P<0.001)。各组间的踝臂指数值差异有显著性(P=0.000);评价踝臂指数对三支或左主干病变预测价值的操作者工作特征曲线下面积为0.8219,面积的标准误Se=0.0415,(u=7.7518,P=0.0000);踝臂指数≤0.9作为界限值预测三支或左主干病变具有相对较高的特异度(91.76%)和敏感度(41.38%)。结论新疆维吾尔族患者踝臂指数与冠状动脉狭窄严重程度显著负相关,踝臂指数≤0.90对预测冠状动脉三支或左主干病变具有较高的特异度和敏感度。

Aim To examine the relationship between ankle brachial index and the extent of coronary stenosis and evaluate the value of ankle brachial index to predict the extent of coronary stenosis in Xinjiang Uyghur patients. Methods 114 patients with coronary angiography were examined by ankle brachial index and hemostatic factors evaluation in addition to history, collection. Results Ankle brachial index was inversely and significantly associated with Gensini score（ r = -0. 6941, P 〈 0. 001）. Ankle brachial index was significantly different in all groups （P = 0. 000）. The corresponding area under the receiver operating characteristic curve was 0. 8219,with standard error（Se） = 0.0415, （ u = 7. 7518 ,P =0. 0000） in ankle brachial index in 3-vessel disease or left main coronary, arterial disease. When ankle brachial index ≤0.9, it had a relatively high specificity （91.76%） and sensitivity {41.38% ） for predicting the presence of 3-vessel disease or left main coronary arterial disease. Conclusion In Xinjiang Uyghur patients, ankle brachial index is inversely and significantly associated with the extent of coronary stenosis, and ankle braehial index ≤0.9 has relatively high specificity and sensitivity for predicting the presence of 3-vessel disease or left main coronary arterial disease.