阴道唾液酸酶与细菌性阴道病和妊娠结局的关系

Relationship between vaginal sialidase bacteria vaginosis and pregnant result

目的通过检测阴道唾液酸酶研究细菌性阴道病（BV）对妊娠结局的影响。方法采用泉池细菌性阴道病快速检测试剂对来笔者所在医院分娩的1922例孕妇进行阴道唾液酸酶的检测诊断BV，阴道唾液酸酶阳性诊断为BV，将BV阳性列为研究组，BV阴性为对照组，对比两组的胎膜早破、早产、新生儿感染发生率。结果1922例孕妇中BV检出率为22％，研究组的胎膜早破、早产、新生儿感染发生率分别是36．64％、18．2％、12．29％；明显高于对照组的孕妇的发生率11．87％、4．2％、3．2％。两者比较，差异均有非常显著性（P〈0．001）。结论阴道唾液酸酶检测在BV中的阳性率高，是引起胎膜早破、早产、新生儿感染的主要原因，应重视孕期检查时BV的诊断和治疗。

Objective To study the relationship among vaginal sialidase, bacterial vaginosis （BV） and result pregnancy. Methods Vaginal sialidase was measured by quick bacterial vaginosis detection Kit from 1922 pregnant women in our hospital to labor, the diagnosis of BV was positive of sialidase activity. Incidence of premature rupture of membranes （PROM）, premature delivery, newborn infection with BV（ study group） and normal pregnant（ control group） were contrast. Results Positive, state with was 22% in 1922 cases pregnant. Incidence of premature rupture of membranes, premature delivery, newborn infection in the study group were 36. 64% ,18.2% ,12. 29% ;the study group were significantly higher than the control group 11.87% ,4. 2% ,3.2% o There were significant differences between these two groups （P 〈0. 001 ）. Conclusion Vaginal sialidase activity has strong relation with bacterial vaginosis. Measuring vaginal sialidase activity is a fast, easy, and useful method to diagnose bacterial vaginosis. It also has relation with PROM, premature delivery, newborn infection.