肝硬化CT表现与肝纤维化因子的关系

The relationship between CT performance of liver cirrhosis and liver fibrosis factors

目的 探讨肝纤维化因子的检测数据及其与CT扫描图像表现之间的关系。方法对89例住院患者的CT图像进行肝硬化CT分级：0级（无肝硬化），Ⅰ级，Ⅱ级，Ⅲ级，Ⅳ级。然后与其血清联合检测肝纤维化因子[Ⅲ型前胶原肽（PCⅢ）、Ⅳ型胶原（Ⅳ-C）、层粘连蛋白（LN）、透明质酸（HA）]的检测数据进行对比分析。结果0级无肝硬化患者中，四项指标均无升高；CT表现为Ⅰ级的肝硬化患者中，Ⅳ-C略有升高；CT表现为Ⅱ级的肝硬化患者中，Ⅳ-C、HA略有升高；CT表现为Ⅲ级的肝硬化患者中，Ⅳ-C、HA、LN三项升高，以HA为显著；CT表现为Ⅳ级的肝硬化患者中，四项指标均有显著升高。结论随着肝硬化CT表现的明显，各项肝纤维化因子的升高也显著，两者呈正相关。

Objective To investigate the relationship between CT performance of liver cirrhosis and liver fibrosis factors. Methods 89 hospitalized patients were graded for the CT performance of the liver cirrhosis ：0 class （ have no cirrhosis） , Ⅰ , Ⅱ ,Ⅲ, Ⅳ class. Then to compare the examination data of serum liver fibrosis factors ：type m procollagen（PⅢP）, Ⅳ collagen（Ⅳ-C） ,laminin（LN） ,hyaluronic acid（HA）. Results 0 class（have no cirrhosis in the sufferer） ：four index signs all has no increase. Ⅰ class：the Ⅳ-C slightly goes up. Ⅱclass：iv-C,the HA slightly goes up. Ⅲ class：the three of Ⅳ-C, HA, LN rises,the HA is distinct. Ⅳ class：four index signs all go up obviously. Conclusion With the CT performance of liver cirrhosis is obvious, the liver fibrosis factors get obvious, too. Both of them get positive correlation.