医用高分子材料的Ames试验研究

THE STUDY OF THE MEDICAL HIGH POLYMERS MATERIALS IN AMES TEST

男性绝育药输精管粘堵剂、男性避孕材料水凝胶、医用组织复合膜、胶原膜、复合缝线、铬制复合型可吸收缝线、药物载体聚乳酸、固定材料聚酯醚等８种医用高分子材料，经Ａｍｅｓ试验的标准菌株ＴＡ９７、ＴＡ９８、ＴＡ１００、ＴＡ１０２测试，均未诱发回复突变菌落数增加，对Ａｍｅｓ试验菌株无诱发突变作用。

The study is detected that dury on spermatic duct adhesive for male sterilization, Hydrogel HFMC for male sterilization, Co membranes in medical organize, collagen membranes, Co suture, absorbed CrCo stuture, dury carried Polymile acid and Solid material Polyesterether would not be to induce positive mutation for Ames test. The results demonstrated that 8 medical high polymers material would not be mutagenic in this experiment. It is feasible that Ames test is detected each type medical high polymers material.