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新疆地区汉族人群感染幽门螺杆菌vacA亚型分布特征 被引量:1

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摘要 幽门螺杆菌(Helicobacter pylori,Hp)毒素相关蛋白基因(cagA)和细胞空泡毒素基因(vacA)是Hp的重要致病基因,本研究对新疆地区汉族慢性浅表性胃炎、慢性萎缩性胃炎、胃溃疡、胃癌患者感染坳的vacA基因型进行测定,探讨新疆地区汉族人群HpvacA基因型分布及与胃疾病的关系。
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2009年第3期263-264,共2页 Chinese Journal of Microbiology and Immunology
基金 新疆维吾尔自治区科技厅自然科学基金资助项目(200521109)
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同被引文献7

  • 1华晔,张尤历,杨大明.中国镇江地区幽门螺杆菌vacA基因型状况及其与胃十二指肠疾病关系的研究[J].江苏大学学报(医学版),2005,15(4):312-315. 被引量:5
  • 2周曾芬,代薇,张建中,南琼,张静祎,王健,金利,和泽元,陶中原,木金花.云南汉、白、纳西族人群幽门螺杆菌vacA基因m混合亚型及iceA基因混合型的致病性研究[J].中华医学杂志,2005,85(34):2408-2413. 被引量:2
  • 3Yamaoka Y. Mechanisms of disease:Helicobacter pylori virulence factors[J].Nat Rev Gastroenterol Hepatol,2010,(11):629-641.
  • 4Russo F,Berloco P,Cuomo R. Helicobacter pylori strains and histologically-related lesions affect the outcome of triple eradication therapy:a study from southern Italy[J].Alimentary Pharmacology and Therapeutics,2003,(03):421-428.
  • 5Chaudhuri S,Chowdhury A,Datta S. Anti-Helicobacter pylori therapy in India:differences in eradication efficiency associated with particular alleles of vacuolating cytotoxin (vacA) gene[J].Journal of Gastroenterology and Hepatology,2003,(02):190-195.
  • 6Broutet N,Marais A,Lamouliatte H. cagA status and eradication treatment outcome of anti-Helicobacter pylori triple therapies in patients with nonulcer dyspepsia[J].J Cliu Microbiol,2001,(04):1319-1322.
  • 7Atherton JC,Cao P,Peek RM Jr. Mosaieism in vacuolating cytotoxin alleles of Helicobacter pylori.Association of specific vacA types with eytotoxin production and peptie ulceration[J].Journal of Biological Chemistry,1995,(30):17771-17777.

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