摘要
为探索非注射性尿道给药替代海绵体内注射的可行性和安全度，对于３２例阳萎患者采用随机分组、自身前后对照、交叉给药的方法观察经尿道给予前列腺素Ｅ１（ＰＧＥ１）６００μｇ与海绵体内注射ＰＧＥ１１５μｇ的血流动力学作用。认为经尿道给予ＰＧＥ１治疗阳萎疗效确实，安全可靠。其６００μｇ剂量足以产生经海绵体内注射ＰＧＥ１１５μｇ的临床疗效。可在临床推广试用。
n order to probe the feasibility and safety of the substitution of per urethral adiminstration for intra-cavernous injection, the hemodynamic effects of per urethral administion of PGE1 600μg and intra-cavernous injecton of PGE1 15μg were investigated by self-control and cross medicaton randomizely in 32 impotent patients. It showed that per urethral administration of PGE1 had definite curing effects as intracavernous injection on impotence with good feasility and safety.
