摘要
目的探讨螺内酯对慢性充血性心力衰竭(CHF)的临床治疗效果。方法122例患者随机分成观察组(62例)和对照组(60例),两组均予抗心衰常规治疗,如血管转换酶抑制剂卡托普利25～50mg/d、速尿20～100mg/d、消心痛10mg/d,无禁忌证者口服地高辛0.125mg/d,观察组加用螺内酯20～40mg/d,连续用药8周以上。结果观察组与对照组比较左室射血分数、每搏输出量和临床疗效差异有显著性(P<0.05)。结论螺内酯治疗充血性心力衰竭有较好的临床疗效,降低病死率。
Objective To evaluate the effects of spironolactone on chronic congestive heart failure（CHF）. Methods 120 cases of patients were divided into investigation group（62 cases ） and health control group（ 60 eases ）, lowdose spironolactone 20- 40mg a day in investigation group for 8 weeks,with the routine treatment. Results Compared the nvestigation group and the health control group,EF volume,stroke volume in the nvestigation group were significantly increased.In Addition,the clinical manifestations were also improved in spironolactone treatment group（ P 〈 0.05 ）. Conclusion The spironolactone is effective in treating chronic congestive heart failure, which also could decrease the mortality.
出处
《中国现代医生》
2009年第10期28-29,共2页
China Modern Doctor
关键词
心力衰竭
慢性
充血性
螺内酯
Heart failure
Chronic
Congestive
Spironolactone
