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Anal metastasis from recurrent breast lobular carcinoma:A case report 被引量:1

Anal metastasis from recurrent breast lobular carcinoma:A case report
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摘要 We report a case of isolated gastrointestinal metastasis from breast lobular carcinoma,which mimicked primary anal cancer.In July 2000,an 88-year-old woman presented with infiltrating lobular cancer (pT1/G2/N2).The patient received postoperative radiotherapy and hormonal therapy.Four years later, she presented with an anal polypoid lesion.The mass was removed for biopsy.Immunohistochemical staining suggested a breast origin.Radiotherapy was chosen for this patient,which resulted in complete regression of the lesion.The patient died 3 years after the first manifestation of gastrointestinal metastasis. According to the current literature,we consider the immunohistochemistry features that are essential to support the suspicion of gastrointestinal breast metastasis,and since we consider the gastrointestinal involvement as a sign of systemic disease,the therapy should be less aggressive and systemic. We report a case of isolated gastrointestinal metastasis from breast Iobular carcinoma, which mimicked primary anal cancer. In July 2000, an 88-year-old woman presented with infiltrating Iobular cancer (pT1/G2/N2). The patient received postoperative radiotherapy and hormonal therapy. Four years later, she presented with an anal polypoid lesion. The mass was removed for biopsy. Immunohistochemical staining suggested a breast origin. Radiotherapy was chosen for this patient, which resulted in complete regression of the lesion. The patient died 3 years after the first manifestation of gastrointestinal metastasis. According to the current literature, we consider the immunohistochemistry features that are essential to support the suspicion of gastrointestinal breast metastasis, and since we consider the gastrointestinal involvement as a sign of systemic disease, the therapy should be less aggressive and systemic.
机构地区 University of Genova
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第11期1388-1390,共3页 世界胃肠病学杂志(英文版)
关键词 复发性乳腺癌 胃肠道转移 肛门癌 病例报告 内分泌治疗 息肉样病变 系统性疾病 免疫组化染色 Anal cancer Breast cancer InfiltratingIobular carcinoma Estrogen receptors Progesteronereceptors
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