农村儿童少年发病的精神分裂症流行学调查

Epidemiology of childhood and adolescent onset schizophrenia in the rural areas

采用精神卫生１０题筛选表、精神现状检查（ＰＳＥ）和ＣＣＭＤ—２—Ｒ对１４９２３１农村人口做精神疾病流行学调查。发现在５１０例精神分裂症患者中，儿童少年期发病者４３人，占８．４％。男女性别比为１．６８∶１。有精神分裂症家族史２３．３％，男女性别及各年龄组之间无显著性差异。临床痊愈３９．５％，显著进步１４．０％，有不同程度社会功能缺陷４４．２％。从未治疗１６．３％，服药不足２月者１８．６％。结果提示，儿童少年期发病的精神分裂症较少见，男性较多，随年龄增长发病人数增加。在接受精神病专科治疗较少的情况下。

Objective:To study the epidemiology of childhood and adolescent onset schizophrenia in the rural areas of western China. Method:The 10-item Mental Health Checklist,Present State Examination (PSE) and CCMD-2-R were used in the epidemiological survey of a rural population of 149231. Results:43 subjects of childhood or adolescent onset schizophrenia,representing 84% of all schizophrenic cases,were found.The male to female ratio was 168 to 1.Family history was positive in 233% of the subjects with no significant difference between male and female sex and among different age groups.163% had never been treated before while 186% had received less than two months of treatment.395% of subjects were regarded as clinically recovered and 14% having significant improvement.442% had impairment in social functioning of different degrees. Discussion:The current study suggested that childhood and adolescent onset schizophrenia is uncommon among all schizophrenic illnesses.There is male predominance despite unsatisfactory treatment,the clinical and social outcome is not as gloomy as reported in the literature.