颈动脉超声指标与颈动脉及冠状动脉粥样硬化病变的相关性研究

Relationship of Carotid Duplex Scanning Parameters and Carotid and Coronary Artery Atherosclerosis

目的：研究颈动脉二维及多普勒超声指标与颈动脉及冠状动脉粥样硬化病变之间的相关性。材料和方法：前瞻性随机调查１０３例因心绞痛、不明原因胸痛或心肌梗塞而入院行选择性冠状动脉造影的患者，冠脉造影前或造影后１周内行颈动脉超声检查，应用ＳＡＳ统计软件包分析各项颈动脉超声指标与颈动脉粥样硬化及冠状动脉粥样硬化病变之间的相关性。结果：对于早期颈动脉粥样硬化病变，二维超声检测的颈动脉内膜－中层厚度、斑块大小及狭窄程度等指标，可准确反映颈动脉粥样硬化病变情况，且与冠状动脉粥样硬化程度密切相关；而颈动脉多普勒血流频谱指标只有在血管显著狭窄时才有显著性变化。结论：颈动脉超声检测可作为观察全身动脉粥样硬化病变的一个窗口，为早期无创性发现和筛选心脑血管疾病高危患者提供依据。

Purpose:To study the relationship between carotid duplex scanning parameters and carotid or coronary artery atherosclerosis.Materials and Methods:Carotid ultrasound was performed in 103 patients who had been consecutively examined by coronary angiography.Gensini's coronary angiography score was calculated to quantify the extent of coronary atherosclerosis.And Crouse's carotid plaque score was also calculated to quantify the extent of carotid atherosclerosis.Results:For early atherosclerosis,the parameters of B mode ultrasound such as carotid intimal medial thickness,plaque size and stenosis degree,can exactly reflect the carotid atherosclerosis lesions,and they are associated with the degree of coronary atherosclerosis.The carotid blood flow parameters of Doppler ultrasound will not change significantly until the carotid stenosis is severe.Conclusions:Carotid ultrasound can be a “window” of atherosclerosis,and the severity of carotid atherosclerosis may be used as a reference index for the prediction of cardiocerebrovascular disease.