摘要
目的:建立一种稳定,操作简便的肾移植模型。方法:以SD大鼠和Wistar大鼠分别作为供、受体。静脉用临时支架管,将供肾的下腔静脉与受体左肾静脉作端端吻合,供肾腹主动脉与受体腹主动脉端侧吻合,以及输尿管带膀胱瓣与膀胱吻合。结果:建立并改进了大鼠肾移植模型,手术总时间(130±16)min,热缺血时间小于20s,冷缺血时间小于50min,手术成功率90.77%。结论:此模型稳定、可靠,易于掌握。
Objective:To establish a feasible and stable rat model of kidney transplantation. Methods:SD and Wistar rats were used as the donors and the recipients, with the hellp of extradural catheter, the donor inferior vena was anastomosed end-to-end with the recipient left renal vein. An end-to-side anastomosis of abdominal aorta was operated. The donor ureter with ureterocystic flap was conducted to the recipient's bladder. Results:A modified rat model of kidney transplantation was successfully established. The average total operation time was(130 ± 20) min. The average time of warm ischemia and cold ischemia was less than 20 s and 50 min respectively. The success rate of operation reached about 90.77 %. Conclusion:This feasible model of kidney transplantalion is feasible and stable.
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2009年第3期310-312,共3页
Journal of Chongqing Medical University
基金
重庆市卫生局课题(No.08-2-83)
关键词
肾移植
大鼠
模型
Kidney transplantion
Rats
Model