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蒙药嘎日迪五味丸中二萜生物碱的基质辅助激光解吸电离飞行时间质谱分析 被引量:5

Analysis of Aconitum Alkaloids in Mongolian Medicine Garidi Wuweiwan by MALDI-TOF-MS
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摘要 采用基质辅助激光解析电离-飞行时间质谱(MALDI-TOF)对蒙药嘎日迪五味丸中的生物碱进行分析和鉴定。通过准确的相对分子质量测定,在嘎日迪五味丸中检测到了双酯型生物碱、单酯生物碱型和脂类生物碱共21种乌头生物碱,为复方中药中乌头生物碱成分的分析提供了一种新的思路。 Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was used for the analysis of the aconitum alkaloids in Mongolian medicine Garidi Wuweiwan (GRDWWW). By exact molecular weight determination, 21 kinds of aconitum alkaloids including monoester-diterpenoid alklaoids, diester-diterpenoid alkaloids, and lipo-alkaloids are detected in GRDWWW. This study is expected to provide a new method for comprehensive analysis alkaloids of proprietary Chinese medicines.
出处 《质谱学报》 EI CAS CSCD 2009年第2期78-82,共5页 Journal of Chinese Mass Spectrometry Society
基金 深圳市科技计划项目(批准号:200528)资助
关键词 辅助激光解吸电离-飞行时间质谱 嘎日迪五味丸 二萜生物碱 MALDI-TOF-MS Garidi wuweiwan diterpenoid alklaoids
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