年轻与老年女性乳腺癌的临床病理比较分析

Study of the clinicopathologic features of breast cancer between young and elderly women

目的:探讨年轻女性乳腺癌的临床病理特点,为年轻女性乳腺癌的诊治提供依据。方法:对病理组织学确诊的年轻(≤35岁)女性乳腺癌181例及老年(≥60岁)女性乳腺癌186例患者的临床病理资料进行回顾性比较分析。结果:年轻女性乳腺癌患者以31～35岁居多,发病部位左乳多于右乳,2组发病位置均以外上象限居多,多为单发,均以浸润性导管癌为主,年轻组患者的肿瘤大小、组织学分级、TNM分期及腋窝淋巴结转移均明显高于老年组(P<0.05)。结论:年轻女性乳腺癌较老年女性乳腺癌侵袭性强,恶性度高。临床应加强对年轻女性乳腺癌的认识和早期诊断。

Objective： To investigate the clinical and pathological features of breast cancer of young women. Methods： The clinical and pathological characteristics of breast carcinoma were compared between young women （≤35 years old, 181 cases） and elder women （≥60 years old, 186 cases）. Results： More tumors were found in left breast, and located in the upper outer quadrant. The major pathological type was invasive ductal carcinoma. There were significant differences in tumor size, histological grading, TNM staging and axillary lymph node metastases （P〈0.05） between young and elderly patients. Conclusions： Compared with the elderly patients, the breast cancer of young patients were more likely to be larger in tumor size, high-grade, high PTNM stage and with axillary lymph node metastases.