离子液体双水相萃取分离四环素的研究

Study on the Aqueous Two-phase Ionic Liquids Extraction Separation Tetracycline

建立了由亲水性离子液体四氟硼酸1-丁基-3-甲基咪唑（[Bmim]BF4）NaH2PO4形成的双水相体系萃取分离四环素的新方法，研究了盐的浓度、离子液体的用量、四环素的加入量、pH值等对四环素萃取率的影响．结果表明：离子液体的量在1．0-2．0ml，四环素的量在1．8ml，NaH2PO4的浓度在33．3％-38．5％（质量分数），离子液体双水相体系对四环素有较高的萃取率大于〉95％．

Established by the hydrophilic ionic liquid tetrafluoroborate 1-butyl-3-methylimidazole （ [ Bmim] BF4） and the formation of NaH2PO4 aqueous two-phase extraction system tetracycline new method to study the concentration of salt, ionic liquids Dosage, the addition of tetracycline volume on the extraction rate of tetracycline. The results show that： the amount of ionic liquids in the 1.0 - 2.0 ml, the amount of tetracycline in 1.8 ml, NaH2PO4 in the concentration of 33.3% to 38.5% （mass）, ionic liquid aqueous two-phase system of tetracycline there is a higher extraction rate （E% 〉95%）.